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Astragaloside IV Protects Hearts from Sepsis Through Mitochondrial Quality Control
Researchers discovered that Astragaloside IV, a compound from traditional Chinese medicine, protects the heart during sepsis by regulating mitochondrial quality control through the DUSP1-PHB2 pathway. Using genetically modified mice and cell studies, they found this compound normalizes mitochondrial function, reduces inflammation, and preserves cardiac structure during septic cardiomyopathy - a serious complication affecting heart function in severe infections.
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