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Common Amino Acid Arginine Slashes Alzheimer's Brain Damage in Animal StudiesBrain Health

Common Amino Acid Arginine Slashes Alzheimer's Brain Damage in Animal Studies

Researchers from Kindai University found that arginine, a widely available and inexpensive amino acid, can significantly reduce the buildup of toxic amyloid-beta proteins linked to Alzheimer's disease. In both fruit fly and mouse models of Alzheimer's, oral arginine lowered harmful protein deposits, reduced brain inflammation, and improved behavioral outcomes. Arginine appears to work as a chemical chaperone, helping proteins maintain their correct shape and preventing the dangerous clumping that damages brain cells. The study also found reduced activity in genes driving neuroinflammation. Because arginine is already considered safe and sold over the counter, researchers believe it could move quickly into clinical trials as an affordable alternative or complement to costly antibody-based Alzheimer's therapies.

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