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Daily Multivitamin Slows Biological Aging by 4 Months in Large Clinical TrialNutrition & Diet

Daily Multivitamin Slows Biological Aging by 4 Months in Large Clinical Trial

A large randomized clinical trial from Mass General Brigham found that taking a daily multivitamin for two years slowed biological aging in older adults, as measured by five DNA-based epigenetic clocks. The effect was equivalent to about four fewer months of biological aging over the study period. Notably, participants whose biological age already exceeded their chronological age at the start showed the greatest benefit. The study, published in Nature Medicine, tracked 958 healthy adults with an average age of 70, comparing multivitamin users against placebo groups. Two of the five clocks tested — those most strongly linked to mortality risk — showed statistically significant slowing. Researchers see this as early but promising evidence that an accessible, low-cost supplement could meaningfully support healthier aging at the cellular level.

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