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Diabetes and Dementia Are More Connected Than You Think — Here's What to KnowLongevity & Aging

Diabetes and Dementia Are More Connected Than You Think — Here's What to Know

Diabetes and dementia share deeper biological links than previously understood. People with diabetes are about 60% more likely to develop dementia, while Alzheimer's itself can raise blood sugar levels, creating a two-way relationship. Insulin resistance — the engine of type 2 diabetes — also impairs brain cells' ability to use glucose for energy, a pattern some researchers call type 3 diabetes. Blood vessel damage, brain inflammation, and a weakened blood-brain barrier connect both conditions. Excitingly, common diabetes medications like metformin and GLP-1 drugs such as semaglutide (Ozempic) are showing promise in reducing dementia risk, opening new doors for brain protection strategies as we age.

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