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Poor Sleep Linked to Greater Brain White Matter Damage Nearly a Decade LaterBrain Health

Poor Sleep Linked to Greater Brain White Matter Damage Nearly a Decade Later

Researchers tracked over 23,000 middle-aged to older adults and found that specific poor sleep behaviors predicted greater white matter hyperintensity volume on brain MRI nearly nine years later. White matter hyperintensities are small lesions reflecting cerebrovascular damage and are associated with cognitive decline and dementia. Even after accounting for vascular risk factors and lifestyle, three sleep behaviors stood out: sleeping outside the 7–9 hour window, excessive daytime napping, and frequent sleeplessness. Each contributed independently to greater lesion volume. The findings suggest that sleep quality and duration may directly influence brain vascular health over time, offering a potentially modifiable pathway to reduce dementia risk through targeted sleep interventions.

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