This 2026 Cochrane systematic review evaluated 11 randomized controlled trials (4,462 adults) examining how often and in what position patients should be repositioned to prevent pressure injuries. No clear winner emerged among 2-, 3-, 4-, or 6-hourly turning schedules. A wearable sensor providing visual nurse reminders for 2-hourly turns reduced injuries significantly. Prone positioning in ICU patients was linked to roughly 4.5 times more pressure injuries. Micromovement devices during surgery showed promise. Most evidence was rated very low or low certainty due to small sample sizes and poor study design. Cost data from two nursing home trials suggest less frequent turning may save nursing time without worsening outcomes.